Multi-level network modeling of cortical dynamics built on the GENESIS environment

Detailed network modeling integrating knowledge from diierent biological levels of description is important for understanding brain function. To facilitate modeling based on collated experimental connectivity data, we implemented tools in the GENESIS simulation environment for automatic generation, visualization and modiÿcation of network models with units representing cells, layers or cortical areas. As a further integrative step, representations from diierent modeling approaches, multicompartmental cells and integrate-and-ÿre units, could be interfaced in the same model. Development of standardized model description languages would facilitate future integrative eeorts, allowing easy combination of desired models and tools from diierent simulators in one modeling study.